Protective effect of calcitonin on lumbar fusion-induced adjacent-segment disc degeneration in ovariectomized rat

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Protective effect of calcitonin on lumbar fusion-induced adjacent-segment disc degeneration in ovariectomized rat

BACKGROUND Intervertebral disc (IVD) degeneration and pathological changes in the spinal cord are major causes of back pain. In addition to its well-established anti-resorptive effect on bone, calcitonin (CT) potentially exerts protective effects on IVD degeneration in ovariectomized rats. However, possible therapeutic effects of CT on lumbar fusion-induced adjacent-segment disc degeneration (A...

متن کامل

Adjacent segment degeneration following spinal fusion for degenerative disc disease.

Fusion has become the standard of care for numerous pathologic conditions of the spine over the past 50 years. Instrumented thoracolumbar fusion for adolescent and adult spinal deformity has enjoyed great success in arresting the progression of and correcting scoliotic deformity. In the cervical spine, decompression and fusion have provided a greater than 90% likelihood of relieving radicular s...

متن کامل

Does Disc Space Height of Fused Segment Affect Adjacent Disc Degeneration in Anterior Lumbar Interbody Fusion? A Radiological Study

BACKGROUND The restoration of disc space height (DSH) is essential in anterior lumbar interbody fusion (ALIF), while it is unclear whether the reduction of DSH may alter the mechanical status and adversely affect adjacent segment, and few literatures focused on the subject. METHODS Ninety five patients who had undergone ALIF for degenerative disc disease at our institution between March 2004 ...

متن کامل

Adjacent segment degeneration in the lumbar spine.

BACKGROUND A primary concern after posterior lumbar spine arthrodesis is the potential for adjacent segment degeneration cephalad or caudad to the fusion segment. There is controversy regarding the subsequent degeneration of adjacent segments, and we are aware of no long-term studies that have analyzed both cephalad and caudad degeneration following posterior arthrodesis. A retrospective invest...

متن کامل

Protective Effect of Ligustrazine on Lumbar Intervertebral Disc Degeneration of Rats Induced by Prolonged Upright Posture

Most chronic low back pain is the result of degeneration of the lumbar intervertebral disc. Ligustrazine, an alkaloid from Chuanxiong, reportedly is able to relieve pain, suppress inflammation, and treat osteoarthritis and it has the protective effect on cartilage and chondrocytes. Therefore, we asked whether ligustrazine could reduce intervertebral disc degeneration. To determine the effect of...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: BMC Musculoskeletal Disorders

سال: 2015

ISSN: 1471-2474

DOI: 10.1186/s12891-015-0788-7